The enzyme present in almost all tissues that may be separated by electrophoresis into 5 components is:

A common cause of falsely increased LD1 fraction of lactic dehydrogenase is:

The presence of which of the following isoenzymes indicates acute myocardial damage?

In which of the following conditions would a normal level of creatine kinase be found?

Of the following diseases, the one most often associated with elevations of lactate dehydrogenase isoenzymes 4 and 5 on electrophoresis is:

When myocardial infarction occurs, the first enzyme to become elevated is:

A scanning of a CK isoenzyme fractionation revealed 2 peaks: a slow cathodic peak (CKMM and an intermediate peak (CKMB. A possible interpretation for this pattern is:

A 10-year-old was admitted to pediatrics with an initial diagnosis of skeletal muscle disease. The best confirmatory tests would be:

In the immunoinhibition phase of the CKMB procedure:

The presence of increased CKMB activity on a CK electrophoresis pattern is most likely found in a patient suffering from:

Refer to the following illustration: (Pg 102 BOC Book Which of the following is the most likely interpretation of the LD isoenzyme scan illustrated above?

Increaseed serum lactic dehydrogenase activity due to elevation of fast fraction (1 and 2 on elctrophoretic seperation is caused by:

A serum sample drawn in the emergency room from a 42 yr-old man yielded the following laboratory results: patient referance range ck: 185U/L 15-160 U/L AST: 123/U/L 0-48 U/L CKMB: 6U/L 2-12 U/L which of the following conditions might account for these values

Given the following results: alkaline phosphatase: marked increase aspartate amino transferase: slight increase alanine amino transferase: slight increase gamma-glutamyl transferase: slight increase this is most consistent with:

Given the following results: alkaline phosphatase: slight increase aspartate aminotransferase: slight increase alanine aminotransferase: slight increase gamma-glutamyl transferase: slight increase

What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme determination?

Regan isoenzyme has the same properties as alkaline phosphatase that orginates in the

The most heat labile fraction of alkaline phosphatase is obtained from:

The most sensitive enzymatic indicator for liver damage from ethanol intake is:

Isoenzyme assays are performed to improve:

The protein portion of an enzyme complec is called the:

Which of the following chemical determinations may be of help in establishing the presence of seminal fluid?

A 1 year old girl with a hyperlipoproteinemia and lipase deficiency has the following lipid profile: cholesterol: 300mg/dl (7.77 mmol/L LDL: increased HDL: decreased triglycerides: 200 mg/dl chylomicrons: present a serum specimen from this patient that was refrigerated overnight would most likely be:

Chylomicrons are present in which of the following dylipidemias?

Turbidity in serum siggest elevation of:

TSH is prouced by the:

A patient has the followning thyroid profile: total t4: decreased free t4: decreased thyroid peroxidase antibody: positive TSH: decreased

A 45 year old woman complains of fatigue, heat intolerance and hair loss. total free T4 are abnormally low. if the TSH showed marked elevation, this would be consistent with:

The majority if thyroxine (T4 is converted into the more biologically active hormone:

A 2 year old child with decreased serum (T4 is described as being somewhat dwarfed, stocky, overweight, and having coarse features. of the following , the most informative additional laboratory test would be the serum:

The recommended intial thyroid function test for either a healthy asymptomatic patient, or a patient with symptoms which may be related to a thyroid disorder is:

The screening test for congenital hypothyroidism is based upon:

Which one of the following sets of results is consistent with primary hypothyroidism, (eg hishimoto disease result TSH T4 (free thyroxine antimicrosomal antibody Result A decreased decreased positive Result B increased increased positive Result C normal decreased negative Result D increased decreased positive

A 68 yr old female patient tells her physician of being “cold all the time” and recent weight gain, with no change in diet. the doctor orders a TSH level , and the laboratory reports a value of (8.7uU/mL (referance range= 0.5-5.0 uU/mL [0.5-5.o IU/L]. this patient most likely has:

Which of the following is secreted by the placents and used for the early detection of pregnancy?

In amniotic fluid, the procedure used to detect hemolytic disease of the newborn is:

During a normal pregnancy, quantitative human chorionic gonadotropin levels peak at how many weeks after the last menstrual period?

Whi the following steroids is an adrenal cortical hormone?

What common substrate is used in the biosynthesis of adrenal steroids, including androgens and estrogens?

Plasma for cortisol determinations were collected at 7 am, after waking the patient, and at 10 pm that evening. the cortisol level of the morning sample was higher then the evening sample this is consistent with:

Night blindness is associated with deficiency of which of the followng vitamins?

Beriberi is associated with deficiency of vitamin:

Scurvy is assoiciated with defiency of which of the following vitamins?

Rickets is associated with deficiency of which of the following vitamins?

Pellagra is associated witg defiency of which of the following vitamins?

The major action of angiotensin II is:

The urinary excretion product measured as an indicator of epinephrine production is:

Which of the following hormones regulates normal blood calcium levels?

A diagnosisof primary adrenal insufficiency requires demonstration of:

The screen for adrenal cortical hyperfunction with the greatest sensitivity and specificity is:

Which of the following sample collections would give an accurate assessment of potential excess cortisol production (hypercortisolism

Aldosterone is released by the adrenal cortex upon stimulation by:

Clinical assays for tumor markers are most important for:

Detection of which of the following substances is most useful to monitor the course of a patient with testicular cancer?

Increased concentrations of alpha-fetoprotein (AFP in adults are most characteristically associated with:

Carcinoembryonic antigen (CEA is most likely to be produced in a malignany involving the:

Which of the following is useful in the detection and management of carcinoma of the prostate?

Which of the following statements most correctly describes the utility of clinical laboratory assays for tumor markers?

Cancer antigen 125 (CA 125 is a tumor marker associated with:

In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA can occur due to: